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| H | Aragua FC | - | Deportivo Táchira | 1:0 (1:0) | ||
| R | Deportivo Táchira | - | Aragua FC | 2:2 (1:1) | ||
| H: 11.05.2016 20:45 | R: 15.05.2016 22:30 | Sieger: Aragua FC | ||||
| H | Mineros de Guayana | - | Deportivo Anzoátegui | 0:1 (0:0) | ||
| R | Deportivo Anzoátegui | - | Mineros de Guayana | 3:1 (0:1) | ||
| H: 11.05.2016 23:00 | R: 14.05.2016 23:00 | Sieger: Deportivo Anzoátegui | ||||
| H | Caracas FC | - | Deportivo La Guaira | 2:1 (1:0) | ||
| R | Deportivo La Guaira | - | Caracas FC | 0:1 (0:1) | ||
| H: 12.05.2016 01:15 | R: 15.05.2016 21:00 | Sieger: Caracas FC | ||||
| H | Trujillanos FC | - | Zamora FC | 2:3 (1:2) | ||
| R | Zamora FC | - | Trujillanos FC | 0:1 (0:1) | ||
| H: 13.05.2016 01:00 | R: 15.05.2016 23:30 | Sieger: Zamora FC | ||||
