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| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Konyaspor | 18 | 12 | 4 | 2 | 33:14 | 19 | 40 |
| 2 |
|
Trabzonspor | 18 | 11 | 7 | 0 | 33:16 | 17 | 40 |
| 3 |
|
Fenerbahçe | 18 | 11 | 4 | 3 | 33:17 | 16 | 37 |
|
Gaziantep FK | 18 | 10 | 7 | 1 | 33:17 | 16 | 37 | |
| 5 |
|
Antalyaspor | 18 | 10 | 5 | 3 | 33:18 | 15 | 35 |
| 6 |
|
İstanbul Başakşehir | 18 | 11 | 2 | 5 | 27:14 | 13 | 35 |
| 7 |
|
Fatih Karagümrük | 18 | 10 | 5 | 3 | 29:17 | 12 | 35 |
| 8 |
|
Beşiktaş | 18 | 10 | 5 | 3 | 31:22 | 9 | 35 |
| 9 |
|
Hatayspor | 18 | 9 | 5 | 4 | 32:20 | 12 | 32 |
| 10 |
|
Kayserispor | 18 | 9 | 4 | 5 | 29:22 | 7 | 31 |
| 11 |
|
Galatasaray | 18 | 9 | 3 | 6 | 28:21 | 7 | 30 |
| 12 |
|
Adana Demirspor | 18 | 8 | 5 | 5 | 28:17 | 11 | 29 |
| 13 |
|
Kasımpaşa SK | 18 | 8 | 4 | 6 | 34:25 | 9 | 28 |
| 14 |
|
Alanyaspor | 18 | 8 | 4 | 6 | 36:31 | 5 | 28 |
| 15 |
|
Sivasspor | 18 | 6 | 8 | 4 | 26:20 | 6 | 26 |
| 16 |
|
Çaykur Rizespor | 18 | 8 | 2 | 8 | 23:29 | -6 | 26 |
| 17 |
|
Giresunspor | 18 | 7 | 4 | 7 | 22:20 | 2 | 25 |
| 18 |
|
Altay Izmir | 18 | 5 | 4 | 9 | 18:23 | -5 | 19 |
| 19 |
|
Göztepe | 18 | 4 | 2 | 12 | 18:32 | -14 | 14 |
| 20 |
|
Yeni Malatyaspor | 18 | 3 | 3 | 12 | 20:38 | -18 | 12 |
| Champions League | |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
|
# Die Begegnung Gaziantep FK - Yeni Malatyaspor (22. Spieltag) wurde wegen starken Schneefalls in der Halbzeitpause abgebrochen. Die zweite Halbzeit wurde am 23.02.2022 gespielt. |
