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| 15.01.2021 | 17:00 | Gençlerbirliği | - | Fatih Karagümrük | 1:3 (0:2) | |
| 16.01.2021 | 11:30 | Konyaspor | - | Göztepe | 2:3 (0:2) | |
| 14:00 | Gaziantep FK | - | Kayserispor | 2:1 (1:0) | ||
| 14:00 | İstanbul Başakşehir | - | Sivasspor | 1:1 (1:1) | ||
| 17:00 | Antalyaspor | - | Trabzonspor | 1:1 (1:0) | ||
| 17.01.2021 | 11:30 | Denizlispor | - | Hatayspor | 0:2 (0:0) | |
| 14:00 | Yeni Malatyaspor | - | Çaykur Rizespor | 4:1 (0:1) | ||
| 17:00 | Beşiktaş | - | Galatasaray | 2:0 (0:0) | ||
| 18.01.2021 | 17:00 | Fenerbahçe | - | MKE Ankaragücü | 3:1 (2:0) | |
| 17:00 | Kasımpaşa SK | - | BB Erzurumspor | 1:2 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Beşiktaş | 18 | 12 | 2 | 4 | 41:21 | 20 | 38 |
| 2 |
|
Fenerbahçe | 18 | 12 | 2 | 4 | 38:22 | 16 | 38 |
| 3 |
|
Gaziantep FK | 18 | 9 | 7 | 2 | 33:20 | 13 | 34 |
| 4 |
|
Galatasaray | 18 | 10 | 3 | 5 | 34:16 | 18 | 33 |
| 5 |
|
Hatayspor | 18 | 9 | 4 | 5 | 27:22 | 5 | 31 |
| 6 |
|
Alanyaspor | 18 | 9 | 3 | 6 | 29:16 | 13 | 30 |
| 7 |
|
Fatih Karagümrük | 18 | 7 | 6 | 5 | 30:24 | 6 | 27 |
| 8 |
|
Trabzonspor | 18 | 7 | 6 | 5 | 20:21 | -1 | 27 |
| 9 |
|
Antalyaspor | 19 | 6 | 7 | 6 | 20:26 | -6 | 25 |
| 10 |
|
Yeni Malatyaspor | 18 | 6 | 6 | 6 | 25:24 | 1 | 24 |
| 11 |
|
Sivasspor | 18 | 5 | 8 | 5 | 20:22 | -2 | 23 |
| 12 |
|
İstanbul Başakşehir | 18 | 6 | 5 | 7 | 25:29 | -4 | 23 |
| 13 |
|
Konyaspor | 18 | 6 | 4 | 8 | 26:24 | 2 | 22 |
| 14 |
|
Göztepe | 18 | 5 | 7 | 6 | 24:22 | 2 | 22 |
| 15 |
|
Kasımpaşa SK | 18 | 6 | 4 | 8 | 21:29 | -8 | 22 |
| 16 |
|
Çaykur Rizespor | 18 | 5 | 6 | 7 | 23:34 | -11 | 21 |
| 17 |
|
Gençlerbirliği | 18 | 5 | 4 | 9 | 19:34 | -15 | 19 |
| 18 |
|
Kayserispor | 18 | 4 | 4 | 10 | 12:23 | -11 | 16 |
| 19 |
|
BB Erzurumspor | 19 | 4 | 4 | 11 | 18:34 | -16 | 16 |
| 20 |
|
MKE Ankaragücü | 18 | 4 | 3 | 11 | 21:30 | -9 | 15 |
| 21 |
|
Denizlispor | 18 | 3 | 5 | 10 | 17:30 | -13 | 14 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Abstieg |
