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| H | Bayburt İl Özel İdare | - | 1461 Trabzon FK | 0:0 (0:0) | ||
| R | 1461 Trabzon FK | - | Bayburt İl Özel İdare | 0:2 (0:0) | ||
| H: 12.05.2022 15:00 | R: 16.05.2022 14:30 | Sieger: Bayburt İl Özel İdare | ||||
| H | Sivas Belediyespor | - | Bodrum FK | 0:0 (0:0) | ||
| R | Bodrum FK | - | Sivas Belediyespor | 1:0 (0:0) | ||
| H: 12.05.2022 15:00 | R: 16.05.2022 15:00 | Sieger: Bodrum FK | ||||
| H | Tarsus Idman Yurdu | - | Amed SK | 0:0 (0:0) | ||
| R | Amed SK | - | Tarsus Idman Yurdu | 6:7 (0:0, 0:0, 0:0) i.E. | ||
| H: 12.05.2022 19:00 | R: 16.05.2022 19:00 | Sieger: Tarsus Idman Yurdu | ||||
| H | Isparta 32 SK | - | Karacabey Belediyespor | 0:2 (0:1) | ||
| R | Karacabey Belediyespor | - | Isparta 32 SK | 2:1 (0:1) | ||
| H: 12.05.2022 19:00 | R: 16.05.2022 19:00 | Sieger: Karacabey Belediyespor | ||||
