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| 24.04.2022 | Bayburt İl Özel İdare | - | Afjet Afyonspor | 3:0 (2:0) | ||
| 14:00 | Bodrum FK | - | Inegölspor | 0:0 (0:0) | ||
| 14:00 | Çorum FK | - | Niğde Anadolu FK | 2:5 (0:1) | ||
| 14:00 | Etimesgut Belediyespor | - | Turgutluspor | 4:1 (1:0) | ||
| 14:00 | Kahramanmaraşspor | - | Ergene Velimeşe | 1:1 (0:0) | ||
| 14:00 | Sarıyer SK | - | Adıyamanspor | 2:2 (1:0) | ||
| 14:00 | Serik Belediyespor | - | Sakaryaspor | 1:2 (0:1) | ||
| 14:00 | Sivas Belediyespor | - | Diyarbekirspor | 2:0 (0:0) | ||
| 14:00 | Somaspor | - | Ankaraspor | 0:1 (0:1) | ||
| 14:00 | Vanspor FK | - | 1461 Trabzon FK | 0:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Sakaryaspor | 36 | 24 | 9 | 3 | 74:23 | 51 | 81 |
| 2 |
|
Bodrum FK | 36 | 21 | 8 | 7 | 59:24 | 35 | 71 |
| 3 |
|
1461 Trabzon FK | 36 | 21 | 7 | 8 | 60:31 | 29 | 70 |
| 4 |
|
Sivas Belediyespor | 36 | 19 | 9 | 8 | 65:32 | 33 | 66 |
| 5 |
|
Çorum FK | 36 | 17 | 10 | 9 | 53:37 | 16 | 61 |
| 6 |
|
Bayburt İl Özel İdare | 36 | 17 | 9 | 10 | 48:35 | 13 | 60 |
| 7 |
|
Vanspor FK | 36 | 16 | 12 | 8 | 48:42 | 6 | 60 |
| 8 |
|
Afjet Afyonspor | 36 | 17 | 8 | 11 | 61:39 | 22 | 59 |
| 9 |
|
Somaspor | 36 | 15 | 7 | 14 | 49:47 | 2 | 52 |
| 10 |
|
Ankaraspor | 36 | 13 | 12 | 11 | 51:40 | 11 | 51 |
| 11 |
|
Inegölspor | 36 | 14 | 8 | 14 | 49:51 | -2 | 50 |
| 12 |
|
Etimesgut Belediyespor | 36 | 12 | 11 | 13 | 45:51 | -6 | 47 |
| 13 |
|
Diyarbekirspor | 36 | 12 | 5 | 19 | 33:42 | -9 | 41 |
| 14 |
|
Sarıyer SK | 36 | 10 | 10 | 16 | 45:54 | -9 | 40 |
| 15 |
|
Serik Belediyespor | 36 | 11 | 6 | 19 | 44:54 | -10 | 39 |
| 16 |
|
Adıyamanspor | 36 | 11 | 4 | 21 | 43:68 | -25 | 37 |
| 17 |
|
Turgutluspor | 36 | 8 | 10 | 18 | 29:60 | -31 | 34 |
| 18 |
|
Ergene Velimeşe | 36 | 9 | 5 | 22 | 36:71 | -35 | 32 |
| 19 |
|
Niğde Anadolu FK | 36 | 7 | 7 | 22 | 42:79 | -37 | 28 |
| 20 |
|
Kahramanmaraşspor | 36 | 4 | 7 | 25 | 23:77 | -54 | 19 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
