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| 30.11.2021 | 12:55 | Radnički Beograd | - | FK Metalac | 2:3 (0:1, 1:1) i.E. | |
| 01.12.2021 | 13:00 | FK Rad Beograd | - | FK Napredak | 1:0 (1:0) | |
| 13:00 | Radnik Surdulica | - | FK Loznica | 1:2 (0:0) | ||
| 13:00 | TSC Bačka Topola | - | FK Kolubara | 2:1 (1:0) | ||
| 16:15 | Dubočica Leskovac | - | Partizan | 0:1 (0:1) | ||
| 02.12.2021 | 13:00 | FK Novi Pazar | - | OFK Bačka | 2:0 (1:0) | |
| 15:00 | FK Javor | - | Vojvodina | 1:4 (0:0, 1:1) i.E. | ||
| 16.02.2022 | 17:00 | Crvena Zvezda | - | Radnički Niš | 3:2 (0:0, 0:0) i.E. |
