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| 13.03.2021 | 14:00 | FC Gießen | - | VfR Aalen | 0:0 (0:0) | |
| 14:00 | FK Pirmasens | - | FC 08 Homburg | 1:1 (0:0) | ||
| 14:00 | Hessen Kassel | - | SV 07 Elversberg | 0:2 (0:1) | ||
| 14:00 | SSV Ulm 1846 | - | 1. FSV Mainz 05 II | 3:1 (1:0) | ||
| 14:00 | TSG Balingen | - | 1899 Hoffenheim II | 0:1 (0:0) | ||
| 14:00 | TSV Schott Mainz | - | FSV Frankfurt | 0:1 (0:1) | ||
| 14:00 | TSV Steinbach Haiger | - | Kickers Offenbach | 4:0 (2:0) | ||
| 14:00 | VfB Stuttgart II | - | FC-Astoria Walldorf | 3:1 (2:0) | ||
| 14.03.2021 | 14:00 | SC Freiburg II | - | SG Sonnenhof Großaspach | 3:0 (2:0) | |
| 30.03.2021 | 17:30 | Bayern Alzenau | - | Bahlinger SC | 2:3 (1:1) | |
| 06.04.2021 | 19:00 | Eintracht Stadtallendorf | - | Rot-Weiß Koblenz | 0:2 (0:2) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SC Freiburg II | 27 | 17 | 6 | 4 | 68:31 | 37 | 57 |
| 2 |
|
TSV Steinbach Haiger | 27 | 16 | 6 | 5 | 58:28 | 30 | 54 |
| 3 |
|
SSV Ulm 1846 | 27 | 15 | 7 | 5 | 51:24 | 27 | 52 |
| 4 |
|
SV 07 Elversberg | 27 | 14 | 9 | 4 | 63:29 | 34 | 51 |
| 5 |
|
Kickers Offenbach | 27 | 14 | 9 | 4 | 44:19 | 25 | 51 |
| 6 |
|
FSV Frankfurt | 27 | 15 | 6 | 6 | 39:28 | 11 | 51 |
| 7 |
|
VfB Stuttgart II | 27 | 13 | 6 | 8 | 55:32 | 23 | 45 |
| 8 |
|
Bahlinger SC | 27 | 12 | 6 | 9 | 45:51 | -6 | 42 |
| 9 |
|
FC 08 Homburg | 27 | 10 | 9 | 8 | 48:39 | 9 | 39 |
| 10 |
|
TSG Balingen | 27 | 10 | 6 | 11 | 37:35 | 2 | 36 |
| 11 |
|
Rot-Weiß Koblenz | 27 | 10 | 6 | 11 | 31:37 | -6 | 36 |
| 12 |
|
1. FSV Mainz 05 II | 27 | 9 | 7 | 11 | 35:42 | -7 | 34 |
| 13 |
|
FK Pirmasens | 27 | 8 | 10 | 9 | 27:42 | -15 | 34 |
| 14 |
|
FC Gießen | 27 | 8 | 8 | 11 | 28:32 | -4 | 32 |
| 15 |
|
Hessen Kassel | 27 | 8 | 8 | 11 | 38:48 | -10 | 32 |
| 16 |
|
VfR Aalen | 27 | 8 | 8 | 11 | 29:39 | -10 | 32 |
| 17 |
|
1899 Hoffenheim II | 27 | 8 | 6 | 13 | 34:48 | -14 | 30 |
| 18 |
|
SG Sonnenhof Großaspach | 27 | 7 | 7 | 13 | 33:48 | -15 | 28 |
| 19 |
|
FC-Astoria Walldorf | 27 | 7 | 4 | 16 | 31:48 | -17 | 25 |
| 20 |
|
TSV Schott Mainz | 27 | 7 | 4 | 16 | 34:66 | -32 | 25 |
| 21 |
|
Bayern Alzenau | 27 | 5 | 6 | 16 | 31:53 | -22 | 21 |
| 22 |
|
Eintracht Stadtallendorf | 27 | 1 | 6 | 20 | 22:62 | -40 | 9 |
| Aufstieg | |
| Abstieg |
