 |
 |
|
| 12.11.2022 | 23:00 | Guaireña FC | - | Cerro Porteño | 1:3 (0:2) | |
| 23:00 | Tacuary | - | Libertad | 1:0 (0:0) | ||
| 23:00 | Club Olimpia | - | Club Nacional | 1:1 (0:1) | ||
| 13.11.2022 | 21:00 | Sportivo Ameliano | - | Guaraní | 4:2 (0:2) | |
| 21:00 | General Caballero DJLM | - | Sol de América | 0:0 (0:0) | ||
| 21:00 | Resistencia SC | - | 12 de Octubre de Itauguá | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Olimpia | 22 | 15 | 4 | 3 | 42:19 | 23 | 49 |
| 2 |
|
Cerro Porteño | 22 | 14 | 6 | 2 | 32:13 | 19 | 48 |
| 3 |
|
Club Nacional | 22 | 13 | 6 | 3 | 30:16 | 14 | 45 |
| 4 |
|
Libertad | 22 | 10 | 4 | 8 | 35:27 | 8 | 34 |
| 5 |
|
Tacuary | 22 | 9 | 4 | 9 | 27:25 | 2 | 31 |
| 6 |
|
Sportivo Ameliano | 22 | 9 | 2 | 11 | 29:32 | -3 | 29 |
| 7 |
|
General Caballero DJLM | 22 | 8 | 4 | 10 | 26:26 | 0 | 28 |
| 8 |
|
Guaireña FC | 22 | 7 | 6 | 9 | 26:31 | -5 | 27 |
| 9 |
|
Guaraní | 22 | 6 | 5 | 11 | 23:32 | -9 | 23 |
| 10 |
|
Sol de América | 22 | 5 | 6 | 11 | 21:33 | -12 | 21 |
| 11 |
|
Resistencia SC | 22 | 5 | 6 | 11 | 16:32 | -16 | 21 |
| 12 |
|
12 de Octubre de Itauguá | 22 | 3 | 3 | 16 | 16:37 | -21 | 12 |
| Copa Libertadores |
