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| 12.03.2022 | 13:45 | Freiburger FC | - | 1. FC Bruchsal | 7:1 (2:1) | |
| 14:00 | 1. CfR Pforzheim | - | FSV 08 Bietigheim-Bissingen | 0:2 (0:2) | ||
| 14:00 | FV Ravensburg | - | Stuttgarter Kickers | 0:3 (0:1) | ||
| 14:00 | Neckarsulmer Sport-Union | - | Göppinger SV | 1:1 (0:1) | ||
| 14:00 | TSG Backnang | - | FC-Astoria Walldorf II | 4:1 (3:0) | ||
| 14:00 | TSV Ilshofen | - | Sportfreunde Dorfmerkingen | 1:1 (1:1) | ||
| 14:30 | SV Linx | - | FC Nöttingen | 2:2 (0:1) | ||
| 15:30 | FC 08 Villingen | - | SV Oberachern | 1:0 (0:0) | ||
| 15:30 | SSV Reutlingen | - | SGV Freiberg | 0:3 (0:1) | ||
| 13.03.2022 | 15:00 | 1. FC Rielasingen-Arlen | - | FV Lörrach-Brombach | 5:1 (4:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SGV Freiberg | 24 | 18 | 5 | 1 | 77:17 | 60 | 59 |
| 2 |
|
Stuttgarter Kickers | 24 | 18 | 2 | 4 | 53:15 | 38 | 56 |
| 3 |
|
Göppinger SV | 24 | 13 | 5 | 6 | 42:33 | 9 | 44 |
| 4 |
|
TSG Backnang | 24 | 13 | 2 | 9 | 55:35 | 20 | 41 |
| 5 |
|
1. FC Rielasingen-Arlen | 24 | 12 | 5 | 7 | 37:29 | 8 | 41 |
| 6 |
|
FC 08 Villingen | 24 | 12 | 4 | 8 | 45:29 | 16 | 40 |
| 7 |
|
1. CfR Pforzheim | 24 | 12 | 3 | 9 | 41:33 | 8 | 39 |
| 8 |
|
FC Nöttingen | 24 | 11 | 4 | 9 | 47:44 | 3 | 37 |
| 9 |
|
FSV 08 Bietigheim-Bissingen | 24 | 9 | 7 | 8 | 46:35 | 11 | 34 |
| 10 |
|
FV Ravensburg | 24 | 8 | 9 | 7 | 47:40 | 7 | 33 |
| 11 |
|
Neckarsulmer Sport-Union | 24 | 9 | 6 | 9 | 33:37 | -4 | 33 |
| 12 |
|
SV Oberachern | 24 | 10 | 2 | 12 | 40:45 | -5 | 32 |
| 13 |
|
SSV Reutlingen | 24 | 8 | 6 | 10 | 33:35 | -2 | 30 |
| 14 |
|
FC-Astoria Walldorf II | 24 | 8 | 4 | 12 | 34:49 | -15 | 28 |
| 15 |
|
SV Linx | 24 | 7 | 7 | 10 | 28:50 | -22 | 28 |
| 16 |
|
Freiburger FC | 24 | 7 | 5 | 12 | 37:39 | -2 | 26 |
| 17 |
|
Sportfreunde Dorfmerkingen | 24 | 6 | 6 | 12 | 27:51 | -24 | 24 |
| 18 |
|
1. FC Bruchsal | 24 | 5 | 5 | 14 | 27:58 | -31 | 20 |
| 19 |
|
TSV Ilshofen | 24 | 4 | 6 | 14 | 27:55 | -28 | 18 |
| 20 |
|
FV Lörrach-Brombach | 24 | 1 | 5 | 18 | 18:65 | -47 | 8 |
| Aufstieg | |
| Relegation | |
| Abstieg |
