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| 14.11.1990 | Achilles 1894 | - | NAC Breda | 1:2 (1:2) | ||
| SC Cambuur | - | Go Ahead Eagles | 1:2 (0:1) | |||
| MVV | - | FC Utrecht | 0:2 (0:0) | |||
| Quick Boys | - | NEC Nijmegen | 1:2 (1:0) | |||
| 27.11.1990 | Rijnsburgse Boys | - | Dordrecht '90 | 0:2 (0:1) | ||
| 04.12.1990 | EVV Eindhoven | - | FC Wageningen | 1:3 (0:0, 1:1) n.V. | ||
| SC Heracles '74 | - | Telstar | 5:2 (1:1) |
