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| 23.01.2007 | 20:00 | Willem II | - | De Graafschap | 4:2 (3:1) | |
| 20:45 | AZ Alkmaar | - | MVV | 5:0 (4:0) | ||
| 24.01.2007 | 20:00 | Sparta Rotterdam | - | RKC Waalwijk | 2:3 (1:2, 2:2) n.V. | |
| 20:00 | FC Twente | - | NAC Breda | 1:2 (0:1) | ||
| 20:00 | FC Utrecht | - | RBC Roosendaal | 1:0 (0:0) | ||
| 20:45 | AFC Ajax | - | HFC Haarlem | 4:0 (3:0) | ||
| 25.01.2007 | 20:00 | Roda JC Kerkrade | - | AZ Alkmaar (J) | 2:1 (0:1) | |
| 20:45 | PSV Eindhoven | - | Go Ahead Eagles | 3:2 (0:0) |
