 |
 |
|
|
| 27.01.2022 | 18:30 | Pumas UNAM | - | CF Monterrey | 4:2 (1:1) | |
| 14.04.2022 | 18:30 | Atlas Guadalajara | - | Mazatlán FC | 4:1 (1:1) | |
| 15.04.2022 | 18:15 | Club Necaxa | - | Atlético San Luis | 1:2 (0:2) | |
| 19:30 | FC Juárez | - | CF Pachuca | 2:0 (0:0) | ||
| 21:45 | Club Tijuana | - | CF América | 2:0 (1:1) | ||
| 16.04.2022 | 16:00 | Santos Laguna | - | Gallos Blancos | 3:0 (0:0) | |
| 18:15 | Cruz Azul | - | Deportivo Guadalajara | 1:0 (0:0) | ||
| 18:30 | Club León | - | Puebla FC | 5:4 (2:3) | ||
| 27.04.2022 | 18:00 | UANL Tigres | - | Deportivo Toluca | 1:1 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF América | 14 | 9 | 3 | 2 | 29:15 | 14 | 40 |
| 2 |
|
Atlas Guadalajara | 14 | 8 | 5 | 1 | 24:12 | 12 | 40 |
| 3 |
|
Club León | 14 | 9 | 3 | 2 | 24:16 | 8 | 37 |
| 4 |
|
Santos Laguna | 14 | 7 | 5 | 2 | 29:14 | 15 | 35 |
| 5 |
|
Club Tijuana | 14 | 7 | 3 | 4 | 24:22 | 2 | 35 |
| 6 |
|
Deportivo Guadalajara | 14 | 7 | 4 | 3 | 28:16 | 12 | 33 |
| 7 |
|
Pumas UNAM | 14 | 7 | 3 | 4 | 22:17 | 5 | 31 |
| 8 |
|
Cruz Azul | 14 | 6 | 2 | 6 | 16:17 | -1 | 29 |
| 9 |
|
CF Monterrey | 14 | 5 | 2 | 7 | 25:31 | -6 | 28 |
| 10 |
|
Deportivo Toluca | 14 | 4 | 6 | 4 | 20:18 | 2 | 26 |
| 11 |
|
Atlético San Luis | 14 | 6 | 2 | 6 | 21:20 | 1 | 26 |
| 12 |
|
CF Pachuca | 14 | 6 | 0 | 8 | 22:23 | -1 | 25 |
| 13 |
|
UANL Tigres | 14 | 4 | 4 | 6 | 17:27 | -10 | 25 |
| 14 |
|
Club Necaxa | 14 | 4 | 2 | 8 | 19:24 | -5 | 21 |
| 15 |
|
Mazatlán FC | 14 | 2 | 4 | 8 | 14:30 | -16 | 20 |
| 16 |
|
FC Juárez | 14 | 2 | 4 | 8 | 16:24 | -8 | 17 |
| 17 |
|
Puebla FC | 14 | 1 | 5 | 8 | 13:25 | -12 | 17 |
| 18 |
|
Gallos Blancos | 14 | 3 | 1 | 10 | 9:21 | -12 | 17 |
| Playoffs |
