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| H | UANL Tigres | - | Santos Laguna | 2:2 | ||
| R | Santos Laguna | - | UANL Tigres | 1:1 | ||
| H: 10.05.2018 17:00 | R: 13.05.2018 16:00 | Sieger: Santos Laguna | ||||
| H | CF Pachuca | - | CF América | 2:2 | ||
| R | CF América | - | CF Pachuca | 0:3 | ||
| H: 10.05.2018 17:30 | R: 13.05.2018 17:00 | Sieger: CF Pachuca | ||||
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|
|
|
| H | UANL Tigres | - | Santos Laguna | 2:2 | ||
| R | Santos Laguna | - | UANL Tigres | 1:1 | ||
| H: 10.05.2018 17:00 | R: 13.05.2018 16:00 | Sieger: Santos Laguna | ||||
| H | CF Pachuca | - | CF América | 2:2 | ||
| R | CF América | - | CF Pachuca | 0:3 | ||
| H: 10.05.2018 17:30 | R: 13.05.2018 17:00 | Sieger: CF Pachuca | ||||
