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| H | Monarcas Morelia | - | Club León | 3:3 (2:2) | ||
| R | Club León | - | Monarcas Morelia | 1:2 (0:0) | ||
| H: 28.11.2019 02:00 | R: 01.12.2019 02:00 | Sieger: Monarcas Morelia | ||||
| H | Club Necaxa | - | Gallos Blancos | 3:0 (0:0) | ||
| R | Gallos Blancos | - | Club Necaxa | 2:3 (2:0) | ||
| H: 28.11.2019 04:00 | R: 01.12.2019 04:05 | Sieger: Club Necaxa | ||||
| H | CF Monterrey | - | Santos Laguna | 5:2 (2:2) | ||
| R | Santos Laguna | - | CF Monterrey | 1:1 (1:0) | ||
| H: 29.11.2019 02:06 | R: 02.12.2019 02:00 | Sieger: CF Monterrey | ||||
| H | CF América | - | UANL Tigres | 1:2 (1:0) | ||
| R | UANL Tigres | - | CF América | 2:4 (0:3) | ||
| H: 29.11.2019 04:00 | R: 02.12.2019 04:00 | Sieger: CF América | ||||
