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| 25.01.2019 | 22:00 | Cruz Azul Hidalgo | - | Tuzos de la UAZ | 0:1 (0:1) | |
| 26.01.2019 | 02:30 | Atlético Reynosa | - | Alacranes de Durango | 1:1 (0:1) | |
| 03:00 | Coras de Nayarit | - | Dorados UACH | 0:0 (0:0) | ||
| 03:00 | Murciélagos FC | - | Pacific F. C. | 4:1 (2:1) | ||
| 18:00 | Cimarrones de Sonora II | - | Correcaminos UAT II | 0:2 (0:0) | ||
| 18:00 | Coyotes de Tlaxcala | - | CF América II | 1:1 (0:0) | ||
| 19:15 | Deportivo Toluca II | - | Albinegros Orizaba | 3:2 (2:0) | ||
| 22:00 | Real Zamora | - | Tuxtla FC | 2:0 (1:0) | ||
| 23:00 | Tepatitlán | - | Monarcas Morelia II | 1:1 (0:0) | ||
| 23:00 | Yalmakan FC | - | Club Irapuato | 1:1 (1:1) | ||
| 23:00 | Cocodrilos de Tabasco | - | Sporting Canamy | 2:1 (1:0) | ||
| 27.01.2019 | 00:00 | Pioneros de Cancún | - | Pumas UNAM II | 0:0 (0:0) | |
| 17:00 | Deportivo Guadalajara II | - | Loros UCOL | 1:1 (0:0) | ||
| 18:00 | Club Necaxa II | - | Gavilanes de Matamoros | 2:1 (0:0) | ||
| 19:00 | Leones Negros II | - | Tecos Fútbol Club | 0:3 (0:2) | ||
| 29.01.2019 | 00:00 | Reboceros de La Piedad | - | Inter Playa | 2:0 (1:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Club Irapuato | 18 | 13 | 4 | 1 | 32:12 | 20 | 47 |
| 2 |
|
Murciélagos FC | 18 | 12 | 3 | 3 | 38:17 | 21 | 42 |
| 3 |
|
Loros UCOL | 18 | 10 | 3 | 5 | 39:21 | 18 | 39 |
| 4 |
|
Deportivo Guadalajara II | 18 | 9 | 8 | 1 | 31:16 | 15 | 39 |
| 5 |
|
Club Necaxa II | 18 | 9 | 7 | 2 | 22:15 | 7 | 37 |
| 6 |
|
Tuxtla FC | 18 | 10 | 3 | 5 | 32:18 | 14 | 35 |
| 7 |
|
Cruz Azul Hidalgo | 18 | 9 | 4 | 5 | 25:16 | 9 | 35 |
| 8 |
|
Tepatitlán | 18 | 9 | 5 | 4 | 29:21 | 8 | 34 |
| 9 |
|
Atlético Reynosa | 18 | 8 | 5 | 5 | 24:13 | 11 | 33 |
| 10 |
|
Tuzos de la UAZ | 18 | 8 | 7 | 3 | 27:22 | 5 | 33 |
| 11 |
|
Deportivo Toluca II | 18 | 8 | 6 | 4 | 30:22 | 8 | 32 |
| 12 |
|
Gavilanes de Matamoros | 18 | 8 | 4 | 6 | 26:21 | 5 | 30 |
| 13 |
|
Pumas UNAM II | 18 | 8 | 3 | 7 | 26:22 | 4 | 30 |
| 14 |
|
Coras de Nayarit | 18 | 7 | 6 | 5 | 26:23 | 3 | 29 |
| 15 |
|
Real Zamora | 18 | 8 | 3 | 7 | 21:21 | 0 | 29 |
| 16 |
|
Inter Playa | 18 | 7 | 5 | 6 | 23:21 | 2 | 28 |
| 17 |
|
Correcaminos UAT II | 18 | 6 | 5 | 7 | 19:21 | -2 | 26 |
| 18 |
|
Coyotes de Tlaxcala | 18 | 4 | 11 | 3 | 20:19 | 1 | 25 |
| 19 |
|
Tecos Fútbol Club | 18 | 5 | 5 | 8 | 27:28 | -1 | 25 |
| 20 |
|
Dorados UACH | 18 | 5 | 6 | 7 | 17:21 | -4 | 25 |
| 21 |
|
Monarcas Morelia II | 18 | 6 | 5 | 7 | 30:22 | 8 | 24 |
| 22 |
|
Reboceros de La Piedad | 18 | 4 | 6 | 8 | 22:29 | -7 | 22 |
| 23 |
|
Sporting Canamy | 18 | 5 | 5 | 8 | 22:31 | -9 | 21 |
| 24 |
|
Albinegros Orizaba | 18 | 5 | 4 | 9 | 10:23 | -13 | 20 |
| 25 |
|
Cocodrilos de Tabasco | 18 | 3 | 7 | 8 | 19:25 | -6 | 19 |
| 26 |
|
Yalmakan FC | 18 | 3 | 7 | 8 | 20:26 | -6 | 18 |
| 27 |
|
Leones Negros II | 18 | 4 | 4 | 10 | 20:30 | -10 | 17 |
| 28 |
|
CF América II | 18 | 2 | 8 | 8 | 18:29 | -11 | 16 |
| 29 |
|
Pacific F. C. | 18 | 3 | 5 | 10 | 18:42 | -24 | 16 |
| 30 |
|
Pioneros de Cancún | 18 | 1 | 9 | 8 | 15:26 | -11 | 14 |
| 31 |
|
Alacranes de Durango | 18 | 2 | 7 | 9 | 10:23 | -13 | 14 |
| 32 |
|
Cimarrones de Sonora II | 18 | 1 | 2 | 15 | 8:50 | -42 | 5 |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Playoffs | |
| Abstieg |
