 |
 |
|
|
| 01.04.2022 | 00:00 | Club Necaxa | - | Atlético San Luis | 1:2 (0:1) | |
| 05:00 | Club León | - | Cruz Azul | 2:3 (1:1) | ||
| 05:00 | Santos Laguna | - | Puebla FC | 0:0 (0:0) | ||
| 23:45 | CF América | - | FC Juárez | 2:1 (2:0) | ||
| 02.04.2022 | 01:00 | Gallos Blancos | - | Club Tijuana | 0:2 (0:1) | |
| 20:00 | Atlas Guadalajara | - | Deportivo Toluca | 3:2 (1:1) | ||
| 20:00 | Pumas UNAM | - | UANL Tigres | 0:1 (0:1) | ||
| 04.04.2022 | 02:00 | CF Monterrey | - | CF Pachuca | 5:0 (2:0) | |
| 02:00 | Mazatlán FC | - | Deportivo Guadalajara | 0:1 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
CF Monterrey | 14 | 13 | 0 | 1 | 48:11 | 37 | 39 |
| 2 |
|
UANL Tigres | 14 | 10 | 4 | 0 | 38:9 | 29 | 34 |
| 3 |
|
Deportivo Guadalajara | 14 | 10 | 4 | 0 | 23:5 | 18 | 34 |
| 4 |
|
CF América | 14 | 10 | 2 | 2 | 34:11 | 23 | 32 |
| 5 |
|
CF Pachuca | 14 | 9 | 1 | 4 | 25:15 | 10 | 28 |
| 6 |
|
Atlas Guadalajara | 14 | 6 | 5 | 3 | 23:21 | 2 | 23 |
| 7 |
|
Club Tijuana | 14 | 3 | 8 | 3 | 18:23 | -5 | 17 |
| 8 |
|
Pumas UNAM | 14 | 4 | 4 | 6 | 12:12 | 0 | 16 |
| 9 |
|
Deportivo Toluca | 14 | 4 | 4 | 6 | 23:27 | -4 | 16 |
| 10 |
|
Cruz Azul | 14 | 4 | 3 | 7 | 16:25 | -9 | 15 |
| 11 |
|
Gallos Blancos | 14 | 4 | 3 | 7 | 13:24 | -11 | 15 |
| 12 |
|
Atlético San Luis | 14 | 3 | 5 | 6 | 15:26 | -11 | 14 |
| 13 |
|
Puebla FC | 14 | 3 | 3 | 8 | 10:20 | -10 | 12 |
| 14 |
|
Club León | 14 | 3 | 3 | 8 | 15:32 | -17 | 12 |
| 15 |
|
Santos Laguna | 14 | 3 | 2 | 9 | 12:24 | -12 | 11 |
| 16 |
|
Club Necaxa | 14 | 2 | 5 | 7 | 14:28 | -14 | 11 |
| 17 |
|
Mazatlán FC | 14 | 2 | 4 | 8 | 9:26 | -17 | 10 |
| 18 |
|
FC Juárez | 14 | 2 | 2 | 10 | 13:22 | -9 | 8 |
| Playoffs |
