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| 18.09.2022 | 16:00 | F91 Dudelange | - | Etzella Ettelbruck | 4:0 (2:0) | |
| 16:00 | Swift Hesperange | - | CS FOLA Esch | 8:1 (2:0) | ||
| 16:00 | Jeunesse Esch | - | US Hostert | 1:2 (0:0) | ||
| 16:00 | UN Käerjéng | - | Union Titus Pétange | 0:1 (0:0) | ||
| 16:00 | US Mondorf | - | FC Differdange 03 | 0:1 (0:1) | ||
| 16:00 | Victoria Rosport | - | UNA Strassen | 0:0 (0:0) | ||
| 16:00 | FC Wiltz 71 | - | RFCU Luxemburg | 1:1 (0:0) | ||
| 18:30 | Progrès Niedercorn | - | FC Mondercange | 4:0 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
F91 Dudelange | 7 | 7 | 0 | 0 | 24:7 | 17 | 21 |
| 2 |
|
Swift Hesperange | 7 | 6 | 1 | 0 | 29:6 | 23 | 19 |
| 3 |
|
Progrès Niedercorn | 7 | 4 | 1 | 2 | 14:10 | 4 | 13 |
| 4 |
|
FC Differdange 03 | 7 | 3 | 2 | 2 | 14:7 | 7 | 11 |
| 5 |
|
FC Mondercange | 7 | 3 | 2 | 2 | 14:9 | 5 | 11 |
| 6 |
|
RFCU Luxemburg | 7 | 3 | 2 | 2 | 14:11 | 3 | 11 |
| 7 |
|
US Mondorf | 7 | 3 | 0 | 4 | 8:8 | 0 | 9 |
| 8 |
|
UN Käerjéng | 7 | 2 | 3 | 2 | 5:8 | -3 | 9 |
| 9 |
|
Union Titus Pétange | 7 | 2 | 2 | 3 | 12:12 | 0 | 8 |
| 10 |
|
FC Wiltz 71 | 7 | 2 | 2 | 3 | 10:12 | -2 | 8 |
| 11 |
|
UNA Strassen | 7 | 2 | 1 | 4 | 7:14 | -7 | 7 |
| 12 |
|
Etzella Ettelbruck | 7 | 2 | 1 | 4 | 4:14 | -10 | 7 |
| 13 |
|
CS FOLA Esch | 7 | 2 | 1 | 4 | 6:21 | -15 | 7 |
| 14 |
|
Jeunesse Esch | 7 | 1 | 3 | 3 | 5:11 | -6 | 6 |
| 15 |
|
Victoria Rosport | 7 | 0 | 4 | 3 | 7:14 | -7 | 4 |
| 16 |
|
US Hostert | 7 | 1 | 1 | 5 | 7:16 | -9 | 4 |
| Champions League Quali. | |
| Europa Conference League Quali. | |
| Relegation | |
| Abstieg |
