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| H | Udinese Calcio | - | Calcio Catania | 3:2 (1:2) | ||
| R | Calcio Catania | - | Udinese Calcio | 2:1 (1:1) | ||
| H: 23.01.2008 15:00 | R: 30.01.2008 15:00 | Sieger: Calcio Catania | ||||
| H | Sampdoria | - | AS Roma | 1:1 (0:0) | ||
| R | AS Roma | - | Sampdoria | 1:0 (0:0) | ||
| H: 23.01.2008 18:30 | R: 29.01.2008 21:00 | Sieger: AS Roma | ||||
| H | Inter | - | Juventus | 2:2 (0:0) | ||
| R | Juventus | - | Inter | 2:3 (2:2) | ||
| H: 23.01.2008 21:00 | R: 30.01.2008 21:00 | Sieger: Inter | ||||
| H | Lazio Roma | - | ACF Fiorentina | 2:1 (2:1) | ||
| R | ACF Fiorentina | - | Lazio Roma | 1:2 (1:1) | ||
| H: 24.01.2008 21:00 | R: 30.01.2008 17:45 | Sieger: Lazio Roma | ||||
