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| 11.04.2010 | 18:00 | Ergotelis | - | PAS Giannina | 3:1 (1:0) | |
| 18:00 | PAOK Saloniki | - | AO Kavala | 1:0 (1:0) | ||
| 18:00 | Panathinaikos | - | Iraklis Saloniki | 2:0 (2:0) | ||
| 18:00 | Panionios GSS | - | AE Lárissa | 0:3 (0:2) | ||
| 18:00 | Skoda Xanthi | - | Atromitos | 2:1 (1:0) | ||
| 18:00 | Levadiakos | - | AEK Athen | 0:0 (0:0) | ||
| 18:00 | Panthrakikos | - | Olympiakos Piraeus | 0:2 (0:2) | ||
| 18:00 | Asteras Tripolis | - | Aris Saloniki | 2:1 (2:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Panathinaikos | 29 | 21 | 4 | 4 | 53:17 | 36 | 67 |
| 2 |
|
Olympiakos Piraeus | 29 | 18 | 7 | 4 | 45:17 | 28 | 61 |
| 3 |
|
PAOK Saloniki | 29 | 18 | 5 | 6 | 37:15 | 22 | 59 |
| 4 |
|
AEK Athen | 29 | 14 | 8 | 7 | 41:31 | 10 | 50 |
| 5 |
|
Aris Saloniki | 29 | 12 | 10 | 7 | 34:26 | 8 | 46 |
| 6 |
|
AO Kavala | 29 | 10 | 8 | 11 | 30:31 | -1 | 38 |
| 7 |
|
Iraklis Saloniki | 29 | 10 | 7 | 12 | 37:37 | 0 | 37 |
| 8 |
|
AE Lárissa | 29 | 10 | 7 | 12 | 30:40 | -10 | 37 |
| 9 |
|
Ergotelis | 29 | 9 | 9 | 11 | 36:37 | -1 | 36 |
| 10 |
|
Panionios GSS | 29 | 9 | 9 | 11 | 33:34 | -1 | 36 |
| 11 |
|
Asteras Tripolis | 29 | 10 | 6 | 13 | 29:34 | -5 | 36 |
| 12 |
|
Atromitos | 29 | 9 | 8 | 12 | 31:35 | -4 | 35 |
| 13 |
|
Skoda Xanthi | 29 | 9 | 5 | 15 | 23:34 | -11 | 32 |
| 14 |
|
Levadiakos | 29 | 8 | 7 | 14 | 29:43 | -14 | 31 |
| 15 |
|
PAS Giannina | 29 | 7 | 7 | 15 | 27:45 | -18 | 28 |
| 16 |
|
Panthrakikos | 29 | 3 | 3 | 23 | 20:59 | -39 | 12 |
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