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| 12.02.2022 | 15:00 | Valenciennes FC | - | Toulouse FC | 1:3 (0:1) | |
| 19:00 | AC Ajaccio | - | EA Guingamp | 0:1 (0:0) | ||
| 19:00 | AJ Auxerre | - | AS Nancy Lorraine | 1:1 (1:1) | ||
| 19:00 | Dijon FCO | - | Pau FC | 0:1 (0:0) | ||
| 19:00 | Paris FC | - | US Quevilly-Rouen | 3:0 (2:0) | ||
| 19:00 | Grenoble Foot 38 | - | FC Sochaux | 1:3 (1:1) | ||
| 19:00 | Amiens SC | - | Chamois Niortais | 3:1 (2:0) | ||
| 19:00 | SM Caen | - | Nîmes Olympique | 4:0 (3:0) | ||
| 19:00 | USL Dunkerque | - | Rodez AF | 2:0 (2:0) | ||
| 14.02.2022 | 20:45 | Havre AC | - | SC Bastia | 2:4 (2:2) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Toulouse FC | 24 | 13 | 9 | 2 | 52:21 | 31 | 48 |
| 2 |
|
Paris FC | 24 | 14 | 5 | 5 | 35:20 | 15 | 47 |
| 3 |
|
FC Sochaux | 24 | 12 | 8 | 4 | 28:20 | 8 | 44 |
| 4 |
|
AC Ajaccio | 24 | 12 | 6 | 6 | 21:13 | 8 | 42 |
| 5 |
|
AJ Auxerre | 24 | 10 | 9 | 5 | 36:27 | 9 | 39 |
| 6 |
|
Havre AC | 24 | 8 | 11 | 5 | 24:20 | 4 | 35 |
| 7 |
|
Chamois Niortais | 24 | 10 | 5 | 9 | 28:25 | 3 | 35 |
| 8 |
|
Nîmes Olympique | 24 | 9 | 5 | 10 | 29:31 | -2 | 32 |
| 9 |
|
Pau FC | 24 | 9 | 5 | 10 | 26:28 | -2 | 32 |
| 10 |
|
EA Guingamp | 24 | 7 | 9 | 8 | 26:32 | -6 | 30 |
| 11 |
|
Amiens SC | 24 | 6 | 11 | 7 | 30:23 | 7 | 29 |
| 12 |
|
SM Caen | 24 | 7 | 8 | 9 | 31:27 | 4 | 29 |
| 13 |
|
Dijon FCO | 24 | 9 | 2 | 13 | 29:34 | -5 | 29 |
| 14 |
|
Rodez AF | 24 | 7 | 8 | 9 | 20:25 | -5 | 29 |
| 15 |
|
SC Bastia | 24 | 6 | 10 | 8 | 25:24 | 1 | 28 |
| 16 |
|
US Quevilly-Rouen | 24 | 7 | 7 | 10 | 22:33 | -11 | 28 |
| 17 |
|
Valenciennes FC | 24 | 6 | 8 | 10 | 24:34 | -10 | 26 |
| 18 |
|
Grenoble Foot 38 | 24 | 7 | 4 | 13 | 19:31 | -12 | 25 |
| 19 |
|
USL Dunkerque | 24 | 6 | 6 | 12 | 19:29 | -10 | 24 |
| 20 |
|
AS Nancy Lorraine | 24 | 3 | 8 | 13 | 19:46 | -27 | 17 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
