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| 24.02.2018 | Racing Club de France | - | Girondins Bordeaux | 0:5 | ||
| Stade Rennais | - | US Avranches | 3:0 | |||
| ASPTT Dijon | - | ESTAC Troyes | 0:2 | |||
| 25.02.2018 | Évreux FC 27 | - | Amiens SC | 5:4 i.E. | ||
| US Concarneau | - | Havre AC | 4:3 i.E. | |||
| EA Guingamp | - | Angers SCO | 2:1 | |||
| AS Cherbourg | - | US Orléans | 0:1 | |||
| Stade Brestois 29 | - | FC Nantes | 3:1 | |||
| Tours FC | - | SM Caen | 5:4 i.E. | |||
| FC Chambly | - | Entente SSG | 2:0 | |||
| AC Ajaccio | - | AS Saint-Étienne | 3:2 | |||
| FC Bourg-Péronnas | - | Nîmes Olympique | 5:4 i.E. | |||
| Rodez AF | - | FC Sochaux | 0:3 | |||
| Olympique Marseille | - | OGC Nice | 2:1 | |||
| FC Côte Bleue | - | Toulouse FC | 0:1 | |||
| AS Saint-Priest | - | Paris FC | 5:4 i.E. |
