03.01.1981 Bury FC - Fulham FC 1:1
Liverpool FC - Altrincham FC 4:1
Preston North End - Bristol Rovers 3:4
Southampton FC - Chelsea FC 3:1
Leicester City - Cardiff City 3:0
Notts County - Blackburn Rovers 2:1
Nottingham Forest - Bolton Wanderers 3:3
West Bromwich Albion - Grimsby Town 3:0
Derby County - Bristol City 0:0
Everton FC - Arsenal FC 2:0
Ipswich Town - Aston Villa 1:0
Newcastle United - Sheffield Wednesday 2:1
Manchester City - Crystal Palace 4:0
Queens Park Rangers - Tottenham Hotspur 0:0
Barnsley FC - Torquay United 2:1
Maidstone United - Exeter City 2:4
West Ham United - Wrexham AFC 1:1
Manchester United - Brighton & Hove Albion 2:2
Norwich City - Cambridge United 1:0
Plymouth Argyle - Charlton Athletic 1:2
Hull City - Doncaster Rovers 1:0
Wimbledon FC - Oldham Athletic 0:0
Huddersfield Town - Shrewsbury Town 0:3
Mansfield Town - Carlisle United 2:2
Port Vale FC - Enfield FC 1:1
Leeds United - Coventry City 1:1
Stoke City - Wolverhampton Wanderers 2:2
Peterborough United - Chesterfield FC 1:1
Colchester United - Watford FC 0:1
Birmingham City - Sunderland AFC 1:1
Leyton Orient - Luton Town 1:3
Swansea City - Middlesbrough FC 0:5
Entscheidungsspiele
06.01.1981 Fulham FC - Bury FC 0:0
Bolton Wanderers - Nottingham Forest 0:1
Wrexham AFC - West Ham United 0:0
Oldham Athletic - Wimbledon FC 0:1
Carlisle United - Mansfield Town 2:1
Enfield FC - Port Vale FC 3:0
Coventry City - Leeds United 1:0
Wolverhampton Wanderers - Stoke City 2:1
Chesterfield FC - Peterborough United 1:2
07.01.1981 Bristol City - Derby County 2:0
Tottenham Hotspur - Queens Park Rangers 3:1
Brighton & Hove Albion - Manchester United 0:2
Sunderland AFC - Birmingham City 1:2
12.01.1981 Bury FC - Fulham FC 0:1
19.01.1981 Wrexham AFC - West Ham United 1:0