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| 30.09.2022 | 16:30 | FK Dukla Praha | - | Vysočina Jihlava | 5:0 (2:0) | |
| 17:30 | FK Viagem Příbram | - | Sigma Olomouc B | 5:0 (1:0) | ||
| 18:00 | SFC Opava | - | FK MAS Táborsko | 1:0 (0:0) | ||
| 01.10.2022 | 10:15 | FK Třinec | - | MFK Chrudim | 0:2 (0:0) | |
| 16:00 | SK Líšeň | - | MFK Karviná | 1:2 (0:1) | ||
| 16:00 | 1. SK Prostějov | - | AC Sparta Praha B | 0:2 (0:1) | ||
| 02.10.2022 | 10:15 | Slavia Praha B | - | MFK Vyškov | 3:1 (1:1) | |
| 16:00 | FK Varnsdorf | - | FC Sellier & Bellot Vlašim | 3:1 (1:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SK Líšeň | 10 | 6 | 2 | 2 | 15:5 | 10 | 20 |
| 2 |
|
FK Viagem Příbram | 10 | 5 | 4 | 1 | 19:9 | 10 | 19 |
| 3 |
|
FK Varnsdorf | 10 | 6 | 1 | 3 | 18:12 | 6 | 19 |
| 4 |
|
MFK Vyškov | 10 | 5 | 2 | 3 | 17:12 | 5 | 17 |
| 5 |
|
SFC Opava | 10 | 5 | 1 | 4 | 10:7 | 3 | 16 |
| 6 |
|
MFK Karviná | 10 | 5 | 1 | 4 | 17:16 | 1 | 16 |
| 7 |
|
Sigma Olomouc B | 10 | 4 | 3 | 3 | 11:16 | -5 | 15 |
| 8 |
|
FK Dukla Praha | 10 | 4 | 2 | 4 | 15:11 | 4 | 14 |
| 9 |
|
MFK Chrudim | 10 | 4 | 2 | 4 | 14:11 | 3 | 14 |
| 10 |
|
Vysočina Jihlava | 10 | 4 | 1 | 5 | 13:15 | -2 | 13 |
| 11 |
|
AC Sparta Praha B | 10 | 4 | 1 | 5 | 12:14 | -2 | 13 |
| 12 |
|
FK Třinec | 10 | 3 | 3 | 4 | 13:15 | -2 | 12 |
| 13 |
|
Slavia Praha B | 10 | 3 | 2 | 5 | 16:22 | -6 | 11 |
| 14 |
|
FK MAS Táborsko | 10 | 3 | 2 | 5 | 6:15 | -9 | 11 |
| 15 |
|
1. SK Prostějov | 10 | 2 | 3 | 5 | 13:21 | -8 | 9 |
| 16 |
|
FC Sellier & Bellot Vlašim | 10 | 2 | 0 | 8 | 14:22 | -8 | 6 |
| Aufstieg | |
| Playoffs | |
| Abstieg |
