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| H | Arsenal de Sarandí | - | Deportivo Guadalajara | 0:0 (0:0) | ||
| R | Deportivo Guadalajara | - | Arsenal de Sarandí | 1:3 (1:2) | ||
| H: 11.10.2007 00:30 | R: 26.10.2007 03:30 | Sieger: Arsenal de Sarandí | ||||
| H | São Paulo FC | - | Millonarios | 0:1 (0:0) | ||
| R | Millonarios | - | São Paulo FC | 2:0 (0:0) | ||
| H: 11.10.2007 02:50 | R: 25.10.2007 01:50 | Sieger: Millonarios | ||||
| H | CF América | - | Vasco da Gama - RJ | 2:0 (0:0) | ||
| R | Vasco da Gama - RJ | - | CF América | 1:0 (1:0) | ||
| H: 11.10.2007 02:50 | R: 25.10.2007 01:50 | Sieger: CF América | ||||
| H | Defensor Sporting | - | River Plate | 2:2 (1:2) | ||
| R | River Plate | - | Defensor Sporting | 0:0 (0:0) | ||
| H: 26.10.2007 01:00 | R: 31.10.2007 02:15 | Sieger: River Plate | ||||
