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| H | Monagas | - | Defensor Sporting | 2:0 (0:0) | ||
| R | Defensor Sporting | - | Monagas | 0:2 (0:1) | ||
| H: 05.02.2025 01:30 | R: 12.02.2025 01:30 | Sieger: Monagas | ||||
| H | Club Nacional | - | Alianza Lima | 1:1 (1:0) | ||
| R | Alianza Lima | - | Club Nacional | 3:1 (1:1) | ||
| H: 06.02.2025 01:30 | R: 13.02.2025 01:30 | Sieger: Alianza Lima | ||||
| H | Blooming | - | El Nacional | 3:2 (3:1) | ||
| R | El Nacional | - | Blooming | 4:3 (0:1, 2:1) i.E. | ||
| H: 07.02.2025 01:30 | R: 14.02.2025 01:30 | Sieger: El Nacional | ||||
