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| H | Real Garcilaso | - | Santa Fe | 1:3 (0:2) | ||
| R | Santa Fe | - | Real Garcilaso | 2:0 (1:0) | ||
| H: 23.05.2013 00:45 | R: 29.05.2013 03:00 | Sieger: Santa Fe | ||||
| H | Fluminense RJ | - | Club Olimpia | 0:0 (0:0) | ||
| R | Club Olimpia | - | Fluminense RJ | 2:1 (2:1) | ||
| H: 23.05.2013 03:00 | R: 30.05.2013 03:00 | Sieger: Club Olimpia | ||||
| H | Club Tijuana | - | Atlético Mineiro | 2:2 (1:0) | ||
| R | Atlético Mineiro | - | Club Tijuana | 1:1 (1:1) | ||
| H: 24.05.2013 02:30 | R: 31.05.2013 03:00 | Sieger: Atlético Mineiro | ||||
| H | Boca Juniors | - | Newell's Old Boys | 0:0 (0:0) | ||
| R | Newell's Old Boys | - | Boca Juniors | 10:9 (0:0, 0:0, 0:0) i.E. | ||
| H: 24.05.2013 02:30 | R: 30.05.2013 00:30 | Sieger: Newell's Old Boys | ||||
