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| H | Iporá - GO | - | Anápolis FC - GO | 1:1 (1:1) | ||
| R | Anápolis FC - GO | - | Iporá - GO | 0:1 (0:0) | ||
| H: 09.03.2022 19:30 | R: 13.03.2022 20:00 | Sieger: Iporá - GO | ||||
| H | CRAC - GO | - | Goiás - GO | 0:3 (0:0) | ||
| R | Goiás - GO | - | CRAC - GO | 3:0 (0:0) | ||
| H: 09.03.2022 23:30 | R: 13.03.2022 20:00 | Sieger: Goiás - GO | ||||
| H | Goianésia - GO | - | Vila Nova - GO | 1:2 (1:1) | ||
| R | Vila Nova - GO | - | Goianésia - GO | 3:1 (1:1) | ||
| H: 10.03.2022 00:00 | R: 12.03.2022 20:30 | Sieger: Vila Nova - GO | ||||
| H | Morrinhos - GO | - | Atlético Goianiense | 0:1 (0:0) | ||
| R | Atlético Goianiense | - | Morrinhos - GO | 3:0 (1:0) | ||
| H: 10.03.2022 00:30 | R: 12.03.2022 20:30 | Sieger: Atlético Goianiense | ||||
