 |
 |
|
|
| 22.10.2021 | 21:30 | Club San José | - | Club Aurora | 1:4 (0:2) | |
| 23.10.2021 | 01:30 | Oriente Petrolero | - | CD Guabirá | 2:0 (1:0) | |
| 21:00 | The Strongest | - | Real Potosí | 1:0 (1:0) | ||
| 23:15 | Jorge Wilstermann | - | Royal Pari | 4:1 (2:0) | ||
| 24.10.2021 | 01:30 | Nacional Potosí | - | Blooming | 4:0 (3:0) | |
| 21:00 | Independiente Petrolero | - | Real Tomayapo | 1:0 (0:0) | ||
| 23:15 | Atlético Palmaflor | - | Always Ready | 0:1 (0:0) | ||
| 25.10.2021 | 01:30 | Real Santa Cruz | - | Bolívar | 0:3 (0:1) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Always Ready | 23 | 15 | 5 | 3 | 47:19 | 28 | 50 |
| 2 |
|
The Strongest | 23 | 15 | 4 | 4 | 49:22 | 27 | 49 |
| 3 |
|
Independiente Petrolero | 23 | 15 | 4 | 4 | 40:25 | 15 | 49 |
| 4 |
|
Bolívar | 23 | 12 | 7 | 4 | 50:22 | 28 | 43 |
| 5 |
|
Royal Pari | 23 | 13 | 2 | 8 | 49:32 | 17 | 41 |
| 6 |
|
Oriente Petrolero | 23 | 11 | 5 | 7 | 35:22 | 13 | 38 |
| 7 |
|
Jorge Wilstermann | 23 | 11 | 1 | 11 | 50:42 | 8 | 34 |
| 8 |
|
CD Guabirá | 23 | 10 | 4 | 9 | 35:33 | 2 | 34 |
| 9 |
|
Atlético Palmaflor | 23 | 9 | 5 | 9 | 30:32 | -2 | 32 |
| 10 |
|
Nacional Potosí | 23 | 8 | 7 | 8 | 34:35 | -1 | 31 |
| 11 |
|
Real Santa Cruz | 23 | 8 | 4 | 11 | 31:37 | -6 | 28 |
| 12 |
|
Club Aurora | 23 | 8 | 4 | 11 | 29:37 | -8 | 28 |
| 13 |
|
Real Tomayapo | 23 | 7 | 3 | 13 | 20:34 | -14 | 24 |
| 14 |
|
Blooming | 23 | 6 | 3 | 14 | 25:42 | -17 | 21 |
| 15 |
|
Real Potosí | 23 | 5 | 3 | 15 | 23:45 | -22 | 18 |
| 16 |
|
Club San José | 23 | 0 | 1 | 22 | 7:75 | -68 | 1 |
| Copa Libertadores | |
| Copa Sudamericana | |
| Relegation | |
| Abstieg |
