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| 24.09.2021 | 19:00 | 1. SC Feucht | - | Würzburger FV | 1:0 (0:0) | |
| 19:00 | ATSV Erlangen | - | SpVgg Bayern Hof | 6:0 (3:0) | ||
| 19:00 | DJK Gebenbach | - | SV Seligenporten | 2:3 (1:0) | ||
| 25.09.2021 | 14:00 | SpVgg Ansbach | - | TSV Großbardorf | 1:0 (0:0) | |
| 14:00 | DJK Ammerthal | - | 1. FC Sand | 4:0 (3:0) | ||
| 15:00 | DJK Vilzing | - | Eintracht Bamberg | 0:0 (0:0) | ||
| 15:00 | Vatan Spor Aschaffenburg | - | DJK Bamberg | 1:2 (1:1) | ||
| 16:00 | ASV Cham | - | TSV Abtswind | 1:2 (1:1) | ||
| 16:00 | TSV Karlburg | - | ASV Neumarkt | 0:0 (0:0) |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
Eintracht Bamberg | 13 | 10 | 2 | 1 | 38:8 | 30 | 32 |
| 2 |
|
SpVgg Ansbach | 13 | 10 | 1 | 2 | 30:8 | 22 | 31 |
| 3 |
|
DJK Vilzing | 13 | 9 | 1 | 3 | 28:12 | 16 | 28 |
| 4 |
|
DJK Ammerthal | 13 | 8 | 2 | 3 | 35:19 | 16 | 26 |
| 5 |
|
ASV Neumarkt | 13 | 8 | 2 | 3 | 28:16 | 12 | 26 |
| 6 |
|
ATSV Erlangen | 13 | 8 | 2 | 3 | 24:15 | 9 | 26 |
| 7 |
|
1. SC Feucht | 13 | 7 | 3 | 3 | 22:14 | 8 | 24 |
| 8 |
|
TSV Abtswind | 13 | 7 | 2 | 4 | 20:14 | 6 | 23 |
| 9 |
|
DJK Bamberg | 13 | 6 | 1 | 6 | 20:19 | 1 | 19 |
| 10 |
|
SpVgg Bayern Hof | 13 | 5 | 2 | 6 | 29:33 | -4 | 17 |
| 11 |
|
TSV Großbardorf | 13 | 5 | 1 | 7 | 20:24 | -4 | 16 |
| 12 |
|
DJK Gebenbach | 13 | 4 | 1 | 8 | 25:33 | -8 | 13 |
| 13 |
|
TSV Karlburg | 13 | 2 | 6 | 5 | 10:20 | -10 | 12 |
| 14 |
|
1. FC Sand | 13 | 3 | 3 | 7 | 13:27 | -14 | 12 |
| 15 |
|
ASV Cham | 13 | 2 | 2 | 9 | 16:34 | -18 | 8 |
| 16 |
|
Vatan Spor Aschaffenburg | 13 | 2 | 1 | 10 | 11:31 | -20 | 7 |
| 17 |
|
SV Seligenporten | 13 | 2 | 1 | 10 | 15:36 | -21 | 7 |
| 18 |
|
Würzburger FV | 13 | 2 | 1 | 10 | 12:33 | -21 | 7 |
| Aufstieg | |
| Playoffs | |
| Relegation | |
| Abstieg |
