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| 04.11.2022 | 18:30 | SV Darmstadt 98 | - | Hannover 96 | 1:0 (0:0) | |
| 18:30 | Hansa Rostock | - | SV Sandhausen | 0:1 (0:1) | ||
| 05.11.2022 | 13:00 | 1. FC Heidenheim 1846 | - | SC Paderborn 07 | 3:0 (1:0) | |
| 13:00 | Fortuna Düsseldorf | - | FC St. Pauli | 1:0 (1:0) | ||
| 13:00 | Karlsruher SC | - | Holstein Kiel | 1:4 (0:2) | ||
| 20:30 | Arminia Bielefeld | - | 1. FC Kaiserslautern | 2:3 (0:0) | ||
| 06.11.2022 | 13:30 | Hamburger SV | - | Jahn Regensburg | 3:1 (1:1) | |
| 13:30 | 1. FC Nürnberg | - | 1. FC Magdeburg | 1:2 (0:0) | ||
| 13:30 | Eintracht Braunschweig | - | SpVgg Greuther Fürth | 0:1 (0:1) |
| » Tabelle | Heim | Auswärts | Hinrunde | Rückrunde | 1. Halbzeit | 2. Halbzeit |
| # | Mannschaft | Sp. | S. | U. | N. | Tore | Dif. | Pk. | |
|---|---|---|---|---|---|---|---|---|---|
| 1 |
|
SV Darmstadt 98 | 15 | 9 | 5 | 1 | 25:14 | 11 | 32 |
| 2 |
|
Hamburger SV | 15 | 10 | 1 | 4 | 25:16 | 9 | 31 |
| 3 |
|
1. FC Heidenheim 1846 | 15 | 7 | 6 | 2 | 24:13 | 11 | 27 |
| 4 |
|
SC Paderborn 07 | 15 | 8 | 2 | 5 | 34:18 | 16 | 26 |
| 5 |
|
Fortuna Düsseldorf | 15 | 8 | 2 | 5 | 25:16 | 9 | 26 |
| 6 |
|
Hannover 96 | 15 | 7 | 3 | 5 | 22:17 | 5 | 24 |
| 7 |
|
1. FC Kaiserslautern (N) | 15 | 5 | 8 | 2 | 25:22 | 3 | 23 |
| 8 |
|
Holstein Kiel | 15 | 6 | 5 | 4 | 29:27 | 2 | 23 |
| 9 |
|
Jahn Regensburg | 15 | 5 | 3 | 7 | 15:24 | -9 | 18 |
| 10 |
|
Karlsruher SC | 15 | 5 | 2 | 8 | 22:24 | -2 | 17 |
| 11 |
|
Eintracht Braunschweig (N) | 15 | 4 | 5 | 6 | 17:24 | -7 | 17 |
| 12 |
|
Hansa Rostock | 15 | 5 | 2 | 8 | 15:22 | -7 | 17 |
| 13 |
|
1. FC Magdeburg (N) | 15 | 5 | 2 | 8 | 19:29 | -10 | 17 |
| 14 |
|
SpVgg Greuther Fürth (A) | 15 | 3 | 7 | 5 | 20:25 | -5 | 16 |
| 15 |
|
SV Sandhausen | 15 | 4 | 4 | 7 | 16:21 | -5 | 16 |
| 16 |
|
FC St. Pauli | 15 | 3 | 6 | 6 | 19:21 | -2 | 15 |
| 17 |
|
1. FC Nürnberg | 15 | 4 | 3 | 8 | 13:23 | -10 | 15 |
| 18 |
|
Arminia Bielefeld (A) | 15 | 3 | 2 | 10 | 18:27 | -9 | 11 |
| Aufstieg | |
| Relegation | |
| Relegation | |
| Abstieg |
